Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.510 Biomarker PSYGENET Proportion of reactive airway disease, obstructive pulmonary disease, and pre-existing anxiety disorder or bipolar disorder were significantly increased in persons carrying AAT non-M polymorphisms compared to normal MM genotype (respectively, 10, 20, 21, and 33% compared to 8, 12, 11, and 9%; contingency table, pulmonary: chi2 37, p=0.0001; affective disorder: chi2=171, p=0.0001). 17659342

2007

Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.510 Biomarker CTD_human Proportion of reactive airway disease, obstructive pulmonary disease, and pre-existing anxiety disorder or bipolar disorder were significantly increased in persons carrying AAT non-M polymorphisms compared to normal MM genotype (respectively, 10, 20, 21, and 33% compared to 8, 12, 11, and 9%; contingency table, pulmonary: chi2 37, p=0.0001; affective disorder: chi2=171, p=0.0001). 17659342

2007

Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.510 Biomarker PSYGENET AAT S or Z polymorphisms are present in 25% of persons with anxiety disorder and 42% of persons with bipolar disorder compared to 10% of control group without pre-existing affective disorder. 16870258

2006