Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.590 Biomarker PSYGENET Additionally, at 1, 2, and 8 weeks of treatment, the 21-item Hamilton Depression Rating scores of MDD subjects with POMC ht2 were significantly (P = 0.003-0.044) lower than those of patients with ht1 in subjects those did not experience SLE. 25448875

2015

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.590 Biomarker PSYGENET The following depression-related parameters were determined: plasma ACTH, plasma corticosterone, adrenal gland weight and hippocampal levels of brain-derived neurotrophic factor (BDNF). 24138845

2013

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.590 Biomarker PSYGENET MDD patients carrying the depression-associated AA genotype showed enhanced maximum and area under the curve ACTH and cortisol answers (p = 0.03) as well as an impaired memory and impaired sustained attention performance (p = 0.04) compared to carriers of at least one G allele. 22475622

2013

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.590 Biomarker CTD_human Depression scores at SCL-90 in addicted patients positively correlated with plasma ACTH and cortisol values. 18201294

2008

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.590 Biomarker PSYGENET The demonstration of mRNA POMC in breast carcinoma with NE features suggests a depression and/or an activation of the POMC gene linked to the NE differentiation. 15239795

2005

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.590 Biomarker PSYGENET The expression of both CRFR mRNA in the LC and the plasma level of ACTH increased significantly in "depression-model rats" which exhibit reduced activity following exposure to 14 days forced walking stress (FWS), but not in "spontaneous recovery rats" whose activity was restored after the long-term stress. 12818721

2003