Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8864
Gene Symbol: PER2
PER2
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.450 Biomarker PSYGENET Recent findings concerning the statistical laws of behavioral organization shared between healthy humans and wild-type mice (WT) and their alterations in human depression patients and circadian clock gene (Period 2; Per2) mutant mice indicate that clock genes play functional roles in intermittent, ultradian locomotor dynamics. 23516567

2013

Entrez Id: 8864
Gene Symbol: PER2
PER2
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.450 Biomarker PSYGENET In a cohort of 361 Caucasians, the severity of depression was assessed prospectively during pregnancy (third trimester) and the postpartum period (2-3 days and 6-8 months) using the Edinburgh Postnatal Depression Scale (EPDS). 22721547

2013

Entrez Id: 8864
Gene Symbol: PER2
PER2
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.450 Biomarker PSYGENET The present study is aimed to examine whether functional polymorphic variants, BDNF Val66Met, 5-HTTLPR, or PER2 SNP 10870, are associated with PPD symptoms and whether these genetic polymorphisms interact with season in predicting PPD symptoms. 21997575

2012

Entrez Id: 8864
Gene Symbol: PER2
PER2
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.450 Biomarker PSYGENET In a non-psychiatric cohort of 419 Caucasians, the severity of depression was assessed prospectively during pregnancy (3rd trimester) and the postpartum period (2-3 days and 6-8 months) using the Edinburgh Postnatal Depression Scale. 22209125

2012

Entrez Id: 8864
Gene Symbol: PER2
PER2
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.450 Biomarker PSYGENET Per1, Per2) represent key regulators of circadian rhythmicity, and their targeted disruption in mutant mice produces potentiated reward drive, novelty-seeking, impulsivity, disrupted sleep, reduced depression and anxiety - a behavioral profile highly reminiscent of our selectively bred high responder (bHR) rats compared to bred low responders (bLRs). 21775066

2012