DisGeNET - a database of gene-disease associations

Source: CURATED

Disease: Chemical and Drug Induced Liver Injury ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs10812428

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASDB

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.

19483685

2009

dbSNP:

rs10812428

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASCAT

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.

19483685

2009

dbSNP:

rs10937275

ST6GAL1

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASDB

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.

19483685

2009

dbSNP:

rs10937275

ST6GAL1

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASCAT

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.

19483685

2009

dbSNP:

rs1497546

LOC105373999

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASDB

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.

19483685

2009

dbSNP:

rs1497546

LOC105373999

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASCAT

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.

19483685

2009

dbSNP:

rs2395029

HCP5

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASCAT

Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles.

30661239

2019

dbSNP:

rs2395029

HCP5

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASCAT

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.

19483685

2009

dbSNP:

rs2395029

HCP5

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASDB

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.

19483685

2009

dbSNP:

rs2523822

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASDB

Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles.

21570397

2011

dbSNP:

rs2523822

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASCAT

Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles.

21570397

2011

dbSNP:

rs3129900

TSBP1 ; TSBP1-AS1

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASDB

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury.

20639878

2010

dbSNP:

rs3129900

TSBP1 ; TSBP1-AS1

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASCAT

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury.

20639878

2010

dbSNP:

rs6582630

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASDB

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.

19483685

2009

dbSNP:

rs6582630

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASCAT

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.

19483685

2009

dbSNP:

rs9274407

HLA-DQB1

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASDB

Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles.

21570397

2011

dbSNP:

rs9274407

HLA-DQB1

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.800

GeneticVariation

GWASCAT

Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles.

21570397

2011

dbSNP:

rs10404821

C19orf81

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.700

GeneticVariation

GWASCAT

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.

28043905

2017

dbSNP:

rs11012476

NEBL

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.700

GeneticVariation

GWASCAT

Genome-Wide Association and Replication Study of Hepatotoxicity Induced by Antiretrovirals Alone or with Concomitant Anti-Tuberculosis Drugs.

28388302

2017

dbSNP:

rs112655218

RAB31

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.700

GeneticVariation

GWASCAT

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.

28043905

2017

dbSNP:

rs113206698

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.700

GeneticVariation

GWASCAT

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.

28043905

2017

dbSNP:

rs114577328

HLA-A

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.700

GeneticVariation

GWASCAT

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.

28043905

2017

dbSNP:

rs114811931

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.700

GeneticVariation

GWASCAT

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.

28043905

2017

dbSNP:

rs115266745

LINC01266

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.700

GeneticVariation

GWASCAT

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.

28043905

2017

dbSNP:

rs116561224

CUI:	C4277682
Disease:	Chemical and Drug Induced Liver Injury

Chemical and Drug Induced Liver Injury

0.700

GeneticVariation

GWASCAT

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.

28043905

2017