|
rs1421085
|
|
Obesity
|
C |
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity.
|
23563609 |
2013 |
|
rs1421085
|
|
Obesity
|
C |
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
23563607 |
2013 |
|
rs1421085
|
|
Obesity
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide population-based association study of extremely overweight young adults--the GOYA study.
|
21935397 |
2011 |
|
rs1421085
|
|
Obesity
|
C |
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations.
|
19151714 |
2009 |
|
rs8050136
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
|
23300278 |
2013 |
|
rs8050136
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.900 |
GeneticVariation
|
GWASDB |
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
|
22158537 |
2011 |
|
rs8050136
|
|
Obesity
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide population-based association study of extremely overweight young adults--the GOYA study.
|
21935397 |
2011 |
|
rs8050136
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.900 |
GeneticVariation
|
GWASDB |
In the "obese-type 2 diabetes" scan, FTO variants had the strongest type 2 diabetes effect (rs8050136: relative risk [RR] 1.49 [95% CI 1.34-1.66], P = 1.3 x 10(-13)), with only weak evidence for TCF7L2 (rs7901695 RR 1.21 [1.09-1.35], P = 0.001).
|
19056611 |
2009 |
|
rs8050136
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
A |
0.900 |
GeneticVariation
|
GWASDB |
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.
|
17463248 |
2007 |
|
rs8050136
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
A |
0.900 |
GeneticVariation
|
GWASDB |
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
|
17463249 |
2007 |
|
rs8050136
|
|
Obesity
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants.
|
18159244 |
2007 |
|
rs9939609
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
|
23300278 |
2013 |
|
rs9939609
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
A |
0.900 |
GeneticVariation
|
GWASDB |
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
|
22693455 |
2012 |
|
rs9939609
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
|
21647700 |
2011 |
|
rs9939609
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.900 |
GeneticVariation
|
GWASDB |
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
|
22158537 |
2011 |
|
rs9939609
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.900 |
GeneticVariation
|
GWASDB |
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
|
17463249 |
2007 |
|
rs9939609
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
A |
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
|
17554300 |
2007 |
|
rs17817449
|
|
Obesity
|
|
0.890 |
GeneticVariation
|
GWASDB |
For the binary trait of obesity, we found 16 genome-wide significant signals within the FTO gene (strongest signal at rs17817449, P = 2.5 × 10(-12)).
|
21552555 |
2011 |
|
rs17817449
|
|
Obesity
|
|
0.890 |
GeneticVariation
|
GWASDB |
Genome-wide population-based association study of extremely overweight young adults--the GOYA study.
|
21935397 |
2011 |
|
rs1121980
|
|
Obesity
|
|
0.840 |
GeneticVariation
|
GWASDB |
Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations.
|
21544081 |
2012 |
|
rs1121980
|
|
Obesity
|
|
0.840 |
GeneticVariation
|
GWASDB |
Genome-wide population-based association study of extremely overweight young adults--the GOYA study.
|
21935397 |
2011 |
|
rs1121980
|
|
Obesity
|
T |
0.840 |
GeneticVariation
|
GWASDB |
Six single nucleotide polymorphisms (SNPs) in FTO (fat mass and obesity associated gene) within one linkage disequilibrium (LD) block including the GWA SNP rendering the lowest p-value (rs1121980; log-additive model: nominal p = 1.13 x 10(-7), corrected p = 0.0494; odds ratio (OR)(CT) 1.67, 95% confidence interval (CI) 1.22-2.27; OR(TT) 2.76, 95% CI 1.88-4.03) belonged to the 15 SNPs showing the strongest evidence for association with obesity.
|
18159244 |
2007 |
|
rs1558902
|
|
Obesity
|
A |
0.820 |
GeneticVariation
|
GWASDB |
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
23563607 |
2013 |
|
rs1558902
|
|
Obesity
|
T |
0.820 |
GeneticVariation
|
GWASDB |
Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations.
|
21544081 |
2012 |
|
rs1558902
|
|
Obesity
|
|
0.820 |
GeneticVariation
|
GWASDB |
Genome-wide population-based association study of extremely overweight young adults--the GOYA study.
|
21935397 |
2011 |