Source: GWASDB

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs8050136
rs8050136
FTO
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.900 GeneticVariation GWASDB Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. 23300278

2013
dbSNP: rs8050136
rs8050136
FTO
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.900 GeneticVariation GWASDB Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. 22158537

2011
dbSNP: rs8050136
rs8050136
FTO
CUI: C0028754
Disease: Obesity
Obesity 		0.900 GeneticVariation GWASDB Genome-wide population-based association study of extremely overweight young adults--the GOYA study. 21935397

2011
dbSNP: rs8050136
rs8050136
FTO
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.900 GeneticVariation GWASDB In the "obese-type 2 diabetes" scan, FTO variants had the strongest type 2 diabetes effect (rs8050136: relative risk [RR] 1.49 [95% CI 1.34-1.66], P = 1.3 x 10(-13)), with only weak evidence for TCF7L2 (rs7901695 RR 1.21 [1.09-1.35], P = 0.001). 19056611

2009
dbSNP: rs8050136
rs8050136
FTO
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		A 0.900 GeneticVariation GWASDB A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. 17463248

2007
dbSNP: rs8050136
rs8050136
FTO
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		A 0.900 GeneticVariation GWASDB Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. 17463249

2007
dbSNP: rs8050136
rs8050136
FTO
CUI: C0028754
Disease: Obesity
Obesity 		0.900 GeneticVariation GWASDB Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants. 18159244

2007
dbSNP: rs8050136
rs8050136
FTO
CUI: C1305855
Disease: Body mass index
Body mass index 		A 0.800 GeneticVariation GWASDB In the combined analyses, a significant association was found between rs8050136, located in the first intron of the fat mass and obesity-associated (FTO) gene, and BMI (P = 4.97 × 10(-7)) and FFMI (P = 1.19 × 10(-7)). 21037115

2011
dbSNP: rs8050136
rs8050136
FTO
CUI: C0005910
Disease: Body Weight
Body Weight 		A 0.800 GeneticVariation GWASDB Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260

2009
dbSNP: rs8050136
rs8050136
FTO
CUI: C0005893
Disease: Body mass index procedure
Body mass index procedure 		A 0.700 GeneticVariation GWASDB EMR-linked GWAS study: investigation of variation landscape of loci for body mass index in children. 24348519

2013
dbSNP: rs8050136
rs8050136
FTO
CUI: C0005893
Disease: Body mass index procedure
Body mass index procedure 		0.700 GeneticVariation GWASDB Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population. 23555315

2013
dbSNP: rs8050136
rs8050136
FTO
CUI: C0578022
Disease: Finding of body mass index
Finding of body mass index 		A 0.700 GeneticVariation GWASDB EMR-linked GWAS study: investigation of variation landscape of loci for body mass index in children. 24348519

2013
dbSNP: rs8050136
rs8050136
FTO
CUI: C0578022
Disease: Finding of body mass index
Finding of body mass index 		0.700 GeneticVariation GWASDB Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population. 23555315

2013
dbSNP: rs8050136
rs8050136
FTO
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.700 GeneticVariation GWASDB Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282

2011
dbSNP: rs8050136
rs8050136
FTO
CUI: C1563743
Disease: adiposity
adiposity 		C 0.700 GeneticVariation GWASDB Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. 21706003

2011
dbSNP: rs8050136
rs8050136
FTO
CUI: C1519383
Disease: Smoking Behaviors
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888

2010
dbSNP: rs8050136
rs8050136
FTO
CUI: C0455829
Disease: Waist Circumference
Waist Circumference 		0.700 GeneticVariation GWASDB NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. 19557197

2009
dbSNP: rs8050136
rs8050136
FTO
CUI: C0005893
Disease: Body mass index procedure
Body mass index procedure 		A 0.700 GeneticVariation GWASDB Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260

2009
dbSNP: rs8050136
rs8050136
FTO
CUI: C0578022
Disease: Finding of body mass index
Finding of body mass index 		A 0.700 GeneticVariation GWASDB Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260

2009
dbSNP: rs8050136
rs8050136
FTO
CUI: C0162701
Disease: Polysomnography
Polysomnography 		0.700 GeneticVariation GWASDB Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. 17658951

2007