Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs25487
rs25487
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.040 GeneticVariation BEFREE In conclusion, we found that XRCC1 Arg399Gln genetic variations are associated with pa</span>ncreatic cancer development, whereas the XRCC1 Arg280His and Arg194Trp polymorphisms did not affect pancreatic cancer risk. 27323136

2016

dbSNP: rs25487
rs25487
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.040 GeneticVariation BEFREE Therefore, the meta-analysis suggests that XRCC1 rs25487 polymorphism is associated with pancreatic cancer</span> risk in Asians. 23807675

2013

dbSNP: rs25487
rs25487
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.040 GeneticVariation BEFREE We observed that the minor allele of rs25487 in XRCC1 was significantly associated with PC risk in the per-allele model (odds ratio = 1.29, CI = 1.01-1.65; trend P = 0.043). 22850545

2012

dbSNP: rs25487
rs25487
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.040 GeneticVariation BEFREE We investigated the association between polymorphisms of MGMT (Leu(84)Phe and Ile(143)Val), APE1 (Asp(148)Glu), and XRCC1 (Arg(194)Trp and Arg(399)Gln) and risk of pancreatic cancer in a case-control study. 16844323

2006