|
rs1012068
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Recently, two GWAS variants, MICA rs2596542 and DEPDC5 rs1012068 were identified as being associated with the development of HCV-induced hepatocellular carcinoma (HCC) in Japanese patients.
|
30723271 |
2019 |
|
rs1012068
|
|
|
0.760 |
GeneticVariation |
BEFREE |
There was a significant correlation between DEPDC5 rs1012068A/C and HBV-related HCC in the Han Chinese population.
|
30683632 |
2019 |
|
rs1012068
|
|
|
0.760 |
GeneticVariation |
BEFREE |
After controlling for the influence of sex, smoking and drinking, this study showed a significant relationship between the polymorphism of DEPDC5 rs1012068 and HBV-related HCC.
|
30683632 |
2019 |
|
rs1012068
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Recently, the MICA rs2596542 and DEPDC5 rs1012068 variants in Japanese individuals as well as the HCP5 rs2244546 and PNPLA3 rs738409 variants in European individuals have been found associated with hepatocellular carcinoma (HCC).
|
28928439 |
2017 |
|
rs1012068
|
|
|
0.760 |
GeneticVariation |
BEFREE |
In a Northern Italian discovery cohort (n = 477), neither DEPDC5 rs1012068 nor MICA rs2596542 were associated with HCC (n = 150).
|
26517016 |
2016 |
|
rs1012068
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Rs423058 upstream of PAPL, rs2834167 in IL10RB and rs1012068 in DEPDC5 were associated with chronic HBV status, HBV natural clearance and the presence of HCC (P = 0.0004–0.024), respectively.
|
25032264 |
2014 |
|
rs1012068
|
|
|
0.760 |
GeneticVariation |
BEFREE |
The data also revealed that subjects with the T allele of both SNPs appeared to have a lower susceptibility to HCV-related cirrhosis/HCC than those with the G allele of rs1012068 (p = 0.038, OR = 1.353, 95 % CI 1.017-1.800) and C allele of rs5998152 (p = 0.043, OR = 1.342, 95 % CI 1.010-1.784).
|
25551790 |
2014 |
|
rs5998152
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The data also revealed that subjects with the T allele of both SNPs appeared to have a lower susceptibility to HCV-related cirrhosis/HCC than those with the G allele of rs1012068 (p = 0.038, OR = 1.353, 95 % CI 1.017-1.800) and C allele of rs5998152 (p = 0.043, OR = 1.342, 95 % CI 1.010-1.784).
|
25551790 |
2014 |