Source: ANIMAL_MODELS

CUI Disease Type Disease Class Semantic type DO Class HPO Term Num. genes
C0011853 Diabetes Mellitus, Experimental disease Nutritional and Metabolic Diseases; Endocrine System Diseases Experimental Model of Disease 476
C0035126 Reperfusion Injury disease Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases Injury or Poisoning 231
C0027055 Myocardial Reperfusion Injury phenotype Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases Pathologic Function 161
C0023893 Liver Cirrhosis, Experimental disease Pathological Conditions, Signs and Symptoms; Digestive System Diseases Experimental Model of Disease 140
C0020429 Hyperalgesia phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases Sign or Symptom Abnormality of the nervous system 127
C0011881 Diabetic Nephropathy disease Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases Disease or Syndrome 120
C0376618 Endotoxemia phenotype Pathological Conditions, Signs and Symptoms; Infections Disease or Syndrome 101
C0018800 Cardiomegaly phenotype Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases Finding Abnormality of the cardiovascular system 95
C0014072 Experimental Autoimmune Encephalomyelitis disease Immune System Diseases; Nervous System Diseases Experimental Model of Disease 89
C0024668 Mammary Neoplasms, Experimental phenotype Neoplasms Neoplastic Process; Experimental Model of Disease 81
C0242488 Acute Lung Injury disease Respiratory Tract Diseases Injury or Poisoning 74
C0015934 Fetal Growth Retardation phenotype Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications Disease or Syndrome Growth abnormality 71
C0149721 Left Ventricular Hypertrophy disease Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases Disease or Syndrome Abnormality of the cardiovascular system 70
C0021368 Inflammation phenotype Pathological Conditions, Signs and Symptoms Pathologic Function 69
C0021655 Insulin Resistance phenotype Nutritional and Metabolic Diseases Pathologic Function Abnormality of metabolism/homeostasis 68
C0752308 Hypoxia-Ischemia, Brain disease Nervous System Diseases; Cardiovascular Diseases Disease or Syndrome 67
C2316810 Chronic kidney disease stage 5 disease Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases Disease or Syndrome Abnormality of the genitourinary system 58
C4277682 Chemical and Drug Induced Liver Injury disease Digestive System Diseases; Chemically-Induced Disorders Disease or Syndrome 53
C0023904 Liver Neoplasms, Experimental phenotype Digestive System Diseases; Neoplasms Neoplastic Process; Experimental Model of Disease 49
C0018129 Graft Rejection phenotype Organ or Tissue Function 47
C0242706 Hyperoxia phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 42
C0030193 Pain phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom Constitutional symptom 41
C0038525 Subarachnoid Hemorrhage disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases Disease or Syndrome Abnormality of the nervous system; Abnormality of blood and blood-forming tissues; Abnormality of the cardiovascular system 40
C0036982 Shock, Hemorrhagic phenotype Pathological Conditions, Signs and Symptoms Pathologic Function 38
C0160390 Injury of liver disease Digestive System Diseases; Wounds and Injuries Injury or Poisoning 36