CUI Disease Type Disease Class Semantic type DO Class HPO Term Num. genes
C0011853 Diabetes Mellitus, Experimental disease Nutritional and Metabolic Diseases; Endocrine System Diseases Experimental Model of Disease 472
C0027055 Myocardial Reperfusion Injury phenotype Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases Pathologic Function 161
C0020429 Hyperalgesia phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases Sign or Symptom Abnormality of the nervous system 127
C0023893 Liver Cirrhosis, Experimental disease Pathological Conditions, Signs and Symptoms; Digestive System Diseases Experimental Model of Disease 125
C0011881 Diabetic Nephropathy disease Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases Disease or Syndrome 120
C0376618 Endotoxemia phenotype Pathological Conditions, Signs and Symptoms; Infections Disease or Syndrome 101
C0014072 Experimental Autoimmune Encephalomyelitis disease Immune System Diseases; Nervous System Diseases Experimental Model of Disease 89
C0242488 Acute Lung Injury disease Respiratory Tract Diseases Injury or Poisoning 74
C0021368 Inflammation phenotype Pathological Conditions, Signs and Symptoms Pathologic Function 68
C0021655 Insulin Resistance phenotype Nutritional and Metabolic Diseases Pathologic Function Abnormality of metabolism/homeostasis 66
C0018129 Graft Rejection phenotype Organ or Tissue Function 47
C4277682 Chemical and Drug Induced Liver Injury disease Digestive System Diseases; Chemically-Induced Disorders Disease or Syndrome 44
C0038525 Subarachnoid Hemorrhage disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases Disease or Syndrome Abnormality of the nervous system; Abnormality of blood and blood-forming tissues; Abnormality of the cardiovascular system 40
C0036982 Shock, Hemorrhagic phenotype Pathological Conditions, Signs and Symptoms Pathologic Function 38
C0027814 Neuritis, Autoimmune, Experimental disease Immune System Diseases; Nervous System Diseases Experimental Model of Disease 32
C0162557 Liver Failure, Acute disease Digestive System Diseases Disease or Syndrome Abnormality of the digestive system 23
C0023896 Alcoholic Liver Diseases group Digestive System Diseases; Chemically-Induced Disorders Disease or Syndrome 21
C0006625 Cachexia phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom Growth abnormality 12
C0025295 Meningitis, Pneumococcal disease Infections; Nervous System Diseases Disease or Syndrome 11
C0018781 Noise-induced hearing loss disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases Injury or Poisoning 10
C0600467 Neurogenic Inflammation disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases Injury or Poisoning 7
C0021818 Intervertebral Disk Displacement disease Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases Disease or Syndrome Abnormality of the skeletal system 6
C0267797 Acute hepatitis disease Digestive System Diseases Disease or Syndrome Abnormality of the digestive system; Abnormality of the immune system 6
C0024116 Lung Diseases, Fungal group Infections; Respiratory Tract Diseases Disease or Syndrome 4
C0036974 Shock phenotype Pathological Conditions, Signs and Symptoms Pathologic Function Abnormality of the cardiovascular system 4