Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PLEKHS1 Q5SXH7 pleckstrin homology domain containing S1 2.1E-22 2
MBL1P mannose binding lectin 1, pseudogene 1
RFFL Q8WZ73 ring finger and FYVE like domain containing E3 ubiquitin protein ligase Enzyme 0.41 1
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 90
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 28
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 32
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 58
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 40
IFNG P01579 interferon gamma 0.47 0.288 0.962 25
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 60
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 1
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 15
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 22
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 20
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 7
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 17
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 11
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 76
ALB P02768 albumin Transporter 0.64 0.317 0.962 10
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 45
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 18