Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL6 P05231 interleukin 6 0.32 0.248 0.962 177
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 112
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 110
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 95
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 84
LEP P41159 leptin 0.46 0.349 0.846 78
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 67
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 62
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923 55
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846 53
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769 52
SELE P16581 selectin E 7.9E-10 0.447 0.808 49
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 47
HLA-G P17693 major histocompatibility complex, class I, G 1.4E-11 0.461 0.769 46
PLAUR Q03405 plasminogen activator, urokinase receptor 5.3E-03 0.536 0.731 35
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 34
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769 31
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885 28
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 27
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923 25
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808 25
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885 22
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 22
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 21