Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
OAS2 P29728 2'-5'-oligoadenylate synthetase 2 Enzyme 2.6E-21 0.670 0.538 5
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 14
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769 9
HTR1D P28221 5-hydroxytryptamine receptor 1D G-protein coupled receptor 6.4E-04 0.716 0.308 1
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 11
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692 10
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538 9
HTR3B O95264 5-hydroxytryptamine receptor 3B Ion channel 2.5E-07 0.678 0.423 7
HTR4 Q13639 5-hydroxytryptamine receptor 4 G-protein coupled receptor 2.5E-02 0.610 0.615 6
HTR7 P34969 5-hydroxytryptamine receptor 7 G-protein coupled receptor 4.5E-02 0.592 0.500 4
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 6
ASMT P46597 acetylserotonin O-methyltransferase 1.3E-20 0.691 0.346 3
ATF3 P18847 activating transcription factor 3 Transcription factor 8.9E-02 0.494 0.885 2
ATF4 P18848 activating transcription factor 4 1.6E-02 0.507 0.769 4
APRT P07741 adenine phosphoribosyltransferase 5.5E-13 0.423 0.846 4
ADCY5 O95622 adenylate cyclase 5 1.00 0.617 0.577 5
ADCY7 P51828 adenylate cyclase 7 9.5E-07 0.656 0.462 6
ADCY8 P40145 adenylate cyclase 8 1.8E-06 0.705 0.577 4
ADCYAP1 P18509 adenylate cyclase activating polypeptide 1 Signaling 0.52 0.510 0.846 4
ADRA2A P08913 adrenoceptor alpha 2A G-protein coupled receptor 8.2E-04 0.578 0.615 5
ADRB1 P08588 adrenoceptor beta 1 G-protein coupled receptor 2.9E-06 0.555 0.769 3
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 4
ALG8 Q9BVK2 ALG8 alpha-1,3-glucosyltransferase Enzyme 1.2E-08 0.659 0.577 1
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846 4