Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
GBE1 Q04446 1,4-alpha-glucan branching enzyme 1 Enzyme 1.1E-12 0.612 0.654 1
AGPAT2 O15120 1-acylglycerol-3-phosphate O-acyltransferase 2 1.2E-07 0.585 0.654 3
HPGD P15428 15-hydroxyprostaglandin dehydrogenase 1.4E-05 0.516 0.731 5
CNP P09543 2',3'-cyclic nucleotide 3' phosphodiesterase Enzyme 0.98 0.604 0.692 3
OAS1 P00973 2'-5'-oligoadenylate synthetase 1 Enzyme 3.4E-05 0.626 0.654 6
PAPSS2 O95340 3'-phosphoadenosine 5'-phosphosulfate synthase 2 Enzyme 2.0E-10 0.682 0.462 2
HMGCL P35914 3-hydroxy-3-methylglutaryl-CoA lyase Enzyme 2.6E-06 0.691 0.462 1
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 18
HMGCS1 Q01581 3-hydroxy-3-methylglutaryl-CoA synthase 1 1.00 0.769 0.346 3
HMGCS2 P54868 3-hydroxy-3-methylglutaryl-CoA synthase 2 4.3E-14 0.666 0.577 3
HAAO P46952 3-hydroxyanthranilate 3,4-dioxygenase 1.1E-08 0.644 0.538 1
BDH1 Q02338 3-hydroxybutyrate dehydrogenase 1 Enzyme 7.6E-08 0.729 0.423 2
OXCT1 P55809 3-oxoacid CoA-transferase 1 Enzyme 4.7E-03 0.686 0.423 3
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 16
HOGA1 Q86XE5 4-hydroxy-2-oxoglutarate aldolase 1 Enzyme 1.6E-14 0.792 0.192 2
HPD P32754 4-hydroxyphenylpyruvate dioxygenase Enzyme 5.3E-04 0.573 0.769 1
XRN2 Q9H0D6 5'-3' exoribonuclease 2 0.35 0.821 0.269 1
ALAS1 P13196 5'-aminolevulinate synthase 1 Enzyme 0.11 0.705 0.462 5
ALAS2 P22557 5'-aminolevulinate synthase 2 Enzyme 1.00 0.606 0.577 4
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885 2
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 5
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769 8
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 17
HTR2B P41595 5-hydroxytryptamine receptor 2B G-protein coupled receptor 2.7E-10 0.647 0.538 7