Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ACCS Q96QU6 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Enzyme 9.0E-07 0.522 0.731 161 3
HPGD P15428 15-hydroxyprostaglandin dehydrogenase 1.4E-05 0.516 0.731 194 9
OAS2 P29728 2'-5'-oligoadenylate synthetase 2 Enzyme 2.6E-21 0.670 0.538 38 4
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885 399 8
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 154 15
HMGCS2 P54868 3-hydroxy-3-methylglutaryl-CoA synthase 2 4.3E-14 0.666 0.577 52 9
HIBCH Q6NVY1 3-hydroxyisobutyryl-CoA hydrolase Enzyme 2.6E-13 0.700 0.500 60 10
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808 77 0
NT5C Q8TCD5 5', 3'-nucleotidase, cytosolic 2.7E-03 0.729 0.231 25 0
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885 376 7
HTR1D P28221 5-hydroxytryptamine receptor 1D G-protein coupled receptor 6.4E-04 0.716 0.308 26 1
HTR3C Q8WXA8 5-hydroxytryptamine receptor 3C Ion channel 2.6E-10 0.769 0.192 16 3
HTR5A P47898 5-hydroxytryptamine receptor 5A G-protein coupled receptor 6.3E-03 0.716 0.231 25 6
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 245 30
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808 207 22
PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Kinase 0.25 0.561 0.808 104 1
PTS Q03393 6-pyruvoyltetrahydropterin synthase 6.5E-06 0.636 0.654 89 40
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808 313 38
AKAP10 O43572 A-kinase anchoring protein 10 0.11 0.760 0.308 28 18
AKAP12 Q02952 A-kinase anchoring protein 12 3.6E-02 0.566 0.615 99 8
AKAP3 O75969 A-kinase anchoring protein 3 5.6E-02 0.736 0.269 15 1
AKAP4 Q5JQC9 A-kinase anchoring protein 4 0.99 0.700 0.269 29 0
AKAP6 Q13023 A-kinase anchoring protein 6 1.00 0.695 0.538 34 27
AKAP9 Q99996 A-kinase anchoring protein 9 4.5E-17 0.638 0.385 60 18