Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962 875 79
H3P10 H3 histone pseudogene 10 0.350 0.846 769 0
MIR21 microRNA 21 0.363 0.846 726 2
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962 703 0
IFNA1 P01562 interferon alpha 1 0.371 0.923 662 6
IFNA13 P01562 interferon alpha 13 0.374 0.923 646 4
MIR155 microRNA 155 0.384 0.885 584 1
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808 511 0
MIR146A microRNA 146a 0.398 0.885 505 3
TRBV20OR9-2 T cell receptor beta variable 20/OR9-2 (non-functional) 0.403 0.923 456 0
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 443 160
MIR34A microRNA 34a 0.421 0.846 428 5
IFNB1 P01574 interferon beta 1 0.421 0.846 426 4
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885 421 89
PECAM1 P16284 platelet and endothelial cell adhesion molecule 1 Cell adhesion 0.426 0.846 396 13
MIR145 microRNA 145 0.431 0.846 366 4
IFNA2 P01563 interferon alpha 2 0.442 0.885 355 1
COPD Pulmonary disease, chronic obstructive, severe early-onset 0.456 0.885 349 0
MIR223 microRNA 223 0.433 0.808 348 0
MALAT1 metastasis associated lung adenocarcinoma transcript 1 0.435 0.846 336 5
SRY Q05066 sex determining region Y Transcription factor 0.456 0.808 315 27
H3P23 H3 histone pseudogene 23 0.443 0.769 310 0
MIR126 microRNA 126 0.447 0.846 305 2
MIR221 microRNA 221 0.449 0.846 304 2