Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ACCS Q96QU6 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Enzyme 9.0E-07 0.522 0.731 161 1
HPGD P15428 15-hydroxyprostaglandin dehydrogenase 1.4E-05 0.516 0.731 117 2
OAS1 P00973 2'-5'-oligoadenylate synthetase 1 Enzyme 3.4E-05 0.626 0.654 45 7
OAS2 P29728 2'-5'-oligoadenylate synthetase 2 Enzyme 2.6E-21 0.670 0.538 36 3
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885 396 7
DHCR24 Q15392 24-dehydrocholesterol reductase Enzyme 3.1E-02 0.498 0.769 138 4
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 120 8
HMGCS1 Q01581 3-hydroxy-3-methylglutaryl-CoA synthase 1 1.00 0.769 0.346 9 0
HMGCS2 P54868 3-hydroxy-3-methylglutaryl-CoA synthase 2 4.3E-14 0.666 0.577 38 0
HACD1 B0YJ81 3-hydroxyacyl-CoA dehydratase 1 1.3E-09 0.539 0.846 112 0
HAAO P46952 3-hydroxyanthranilate 3,4-dioxygenase 1.1E-08 0.644 0.538 8 1
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808 66 0
HPD P32754 4-hydroxyphenylpyruvate dioxygenase Enzyme 5.3E-04 0.573 0.769 83 3
XRN1 Q8IZH2 5'-3' exoribonuclease 1 1.00 0.716 0.346 20 1
ALAS1 P13196 5'-aminolevulinate synthase 1 Enzyme 0.11 0.705 0.462 23 3
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885 361 4
NT5C3A Q9H0P0 5'-nucleotidase, cytosolic IIIA Enzyme 1.5E-02 0.593 0.692 73 4
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769 96 8
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 196 21
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808 159 16
PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Kinase 0.25 0.561 0.808 91 1
PFKFB4 Q16877 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 Enzyme 2.1E-09 0.666 0.346 36 0
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808 266 37
AKAP1 Q92667 A-kinase anchoring protein 1 Enzyme 0.74 0.678 0.577 33 0