Source: CGI

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808 4
NT5C2 P49902 5'-nucleotidase, cytosolic II Enzyme 2.1E-06 0.537 0.846 1
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808 1
ARAF P10398 A-Raf proto-oncogene, serine/threonine kinase Kinase 0.96 0.619 0.654 1
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 3
ACVR1 Q04771 activin A receptor type 1 Kinase 0.33 0.535 0.731 1
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 20
AKT2 P31751 AKT serine/threonine kinase 2 Kinase 0.64 0.474 0.769 15
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846 11
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846 1
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 18
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808 2
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846 7
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846 5
ARID2 Q68CP9 AT-rich interaction domain 2 1.00 0.543 0.808 1
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 20
ATP1A1 P05023 ATPase Na+/K+ transporting subunit alpha 1 Transporter 1.00 0.601 0.808 1
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923 16
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808 2
AURKA O14965 aurora kinase A Kinase 0.87 0.475 0.731 2
AXIN1 O15169 axin 1 0.41 0.559 0.577 8
AXIN2 Q9Y2T1 axin 2 0.57 0.507 0.692 8
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 45
BIRC3 Q13489 baculoviral IAP repeat containing 3 Enzyme modulator 6.6E-02 0.491 0.769 4