ROCK1 |
Q13464
|
Rho associated coiled-coil containing protein kinase 1
|
Kinase
|
1.00 |
0.513 |
0.731 |
2
|
1 |
IDH1 |
O75874
|
isocitrate dehydrogenase (NADP(+)) 1
|
|
2.6E-12 |
0.424 |
0.808 |
18
|
2 |
SF3B2 |
Q13435
|
splicing factor 3b subunit 2
|
|
1.00 |
0.780 |
0.308 |
9
|
2 |
XPO1 |
O14980
|
exportin 1
|
Receptor
|
1.00 |
0.504 |
0.692 |
5
|
2 |
RHOA |
P61586
|
ras homolog family member A
|
Enzyme modulator
|
0.60 |
0.502 |
0.808 |
7
|
4 |
FGFR4 |
P22455
|
fibroblast growth factor receptor 4
|
Kinase
|
7.2E-13 |
0.490 |
0.769 |
3
|
4 |
PPP2R1A |
P30153
|
protein phosphatase 2 scaffold subunit Aalpha
|
Enzyme
|
0.98 |
0.588 |
0.577 |
26
|
6 |
FBXW7 |
Q969H0
|
F-box and WD repeat domain containing 7
|
Enzyme modulator
|
1.00 |
0.465 |
0.808 |
18
|
7 |
ERBB3 |
P21860
|
erb-b2 receptor tyrosine kinase 3
|
Kinase
|
1.7E-15 |
0.448 |
0.808 |
12
|
7 |
HERC2 |
O95714
|
HECT and RLD domain containing E3 ubiquitin protein ligase 2
|
|
1.00 |
0.568 |
0.692 |
11
|
9 |
POLE |
Q07864
|
DNA polymerase epsilon, catalytic subunit
|
|
8.0E-27 |
0.526 |
0.731 |
10
|
9 |
SF3B1 |
O75533
|
splicing factor 3b subunit 1
|
Nucleic acid binding
|
1.00 |
0.511 |
0.731 |
8
|
9 |
ESR1 |
P03372
|
estrogen receptor 1
|
Nuclear receptor
|
1.00 |
0.324 |
0.962 |
4
|
11 |
MED12 |
Q93074
|
mediator complex subunit 12
|
Transcription factor
|
1.00 |
0.476 |
0.769 |
25
|
18 |
HRAS |
P01112
|
HRas proto-oncogene, GTPase
|
Enzyme modulator
|
8.0E-02 |
0.378 |
0.885 |
71
|
21 |
ALK |
Q9UM73
|
ALK receptor tyrosine kinase
|
Kinase
|
3.2E-06 |
0.396 |
0.846 |
6
|
21 |
MTOR |
P42345
|
mechanistic target of rapamycin kinase
|
Kinase
|
1.00 |
0.343 |
0.885 |
86
|
26 |
GNAS |
O95467 P63092 P84996 Q5JWF2
|
GNAS complex locus
|
Enzyme modulator
|
0.68 |
0.420 |
0.885 |
60
|
27 |
ERBB2 |
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
6.0E-03 |
0.328 |
0.923 |
23
|
28 |
PIK3CA |
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1.00 |
0.292 |
0.923 |
85
|
55 |
FGFR2 |
P21802
|
fibroblast growth factor receptor 2
|
Kinase
|
1.00 |
0.380 |
0.808 |
82
|
76 |
BTK |
Q06187
|
Bruton tyrosine kinase
|
Kinase
|
1.00 |
0.464 |
0.808 |
8
|
83 |
BRAF |
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1.00 |
0.319 |
0.846 |
125
|
84 |
SMAD4 |
Q13485
|
SMAD family member 4
|
Transcription factor
|
1.00 |
0.401 |
0.808 |
16
|
133 |