ALK |
Q9UM73
|
ALK receptor tyrosine kinase
|
Kinase
|
3.2E-06 |
0.396 |
0.846 |
6
|
21 |
ATM |
Q13315
|
ATM serine/threonine kinase
|
Kinase
|
5.6E-47 |
0.374 |
0.885 |
44
|
888 |
BARD1 |
Q99728
|
BRCA1 associated RING domain 1
|
|
1.4E-24 |
0.597 |
0.538 |
7
|
145 |
BRAF |
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1.00 |
0.319 |
0.846 |
125
|
84 |
BRCA1 |
P38398
|
BRCA1 DNA repair associated
|
Enzyme
|
9.2E-29 |
0.367 |
0.923 |
22
|
2439 |
BRCA2 |
P51587
|
BRCA2 DNA repair associated
|
Nucleic acid binding
|
2.4E-25 |
0.379 |
0.846 |
68
|
2953 |
BRIP1 |
Q9BX63
|
BRCA1 interacting protein C-terminal helicase 1
|
Enzyme
|
6.2E-17 |
0.507 |
0.731 |
15
|
220 |
BTK |
Q06187
|
Bruton tyrosine kinase
|
Kinase
|
1.00 |
0.464 |
0.808 |
8
|
83 |
C11orf65 |
Q8NCR3
|
chromosome 11 open reading frame 65
|
|
2.0E-14 |
0.670 |
0.462 |
32
|
342 |
CHEK2 |
O96017
|
checkpoint kinase 2
|
Kinase
|
1.2E-24 |
0.460 |
0.808 |
48
|
209 |
ERBB2 |
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
6.0E-03 |
0.328 |
0.923 |
23
|
28 |
ERBB3 |
P21860
|
erb-b2 receptor tyrosine kinase 3
|
Kinase
|
1.7E-15 |
0.448 |
0.808 |
12
|
7 |
ESR1 |
P03372
|
estrogen receptor 1
|
Nuclear receptor
|
1.00 |
0.324 |
0.962 |
4
|
11 |
FBXW7 |
Q969H0
|
F-box and WD repeat domain containing 7
|
Enzyme modulator
|
1.00 |
0.465 |
0.808 |
18
|
7 |
FGFR2 |
P21802
|
fibroblast growth factor receptor 2
|
Kinase
|
1.00 |
0.380 |
0.808 |
82
|
76 |
FGFR4 |
P22455
|
fibroblast growth factor receptor 4
|
Kinase
|
7.2E-13 |
0.490 |
0.769 |
3
|
4 |
GNAS |
O95467 P63092 P84996 Q5JWF2
|
GNAS complex locus
|
Enzyme modulator
|
0.68 |
0.420 |
0.885 |
60
|
27 |
HERC2 |
O95714
|
HECT and RLD domain containing E3 ubiquitin protein ligase 2
|
|
1.00 |
0.568 |
0.692 |
11
|
9 |
HRAS |
P01112
|
HRas proto-oncogene, GTPase
|
Enzyme modulator
|
8.0E-02 |
0.378 |
0.885 |
71
|
21 |
IDH1 |
O75874
|
isocitrate dehydrogenase (NADP(+)) 1
|
|
2.6E-12 |
0.424 |
0.808 |
18
|
2 |
MED12 |
Q93074
|
mediator complex subunit 12
|
Transcription factor
|
1.00 |
0.476 |
0.769 |
25
|
18 |
MTOR |
P42345
|
mechanistic target of rapamycin kinase
|
Kinase
|
1.00 |
0.343 |
0.885 |
86
|
26 |
PALB2 |
Q86YC2
|
partner and localizer of BRCA2
|
|
3.0E-19 |
0.485 |
0.769 |
48
|
393 |
PIK3CA |
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1.00 |
0.292 |
0.923 |
85
|
55 |