Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
FLNA P21333 filamin A 1.00 0.456 0.793 361
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.474 0.724 312
FGFR3 P22607 fibroblast growth factor receptor 3 1.8E-05 0.417 0.759 312
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase 1.00 0.352 0.793 303
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.466 0.690 199
FLNB O75369 filamin B 4.9E-10 0.501 0.862 179
PIEZO2 Q9H5I5 piezo type mechanosensitive ion channel component 2 2.3E-06 0.573 0.655 173
PTPN11 Q06124 protein tyrosine phosphatase, non-receptor type 11 1.00 0.429 0.828 168
NSD1 Q96L73 nuclear receptor binding SET domain protein 1 1.00 0.546 0.655 162
FKRP Q9H9S5 fukutin related protein 6.3E-05 0.514 0.586 162
FKTN O75072 fukutin 7.7E-07 0.522 0.586 158
RET P07949 ret proto-oncogene 1.00 0.418 0.724 153
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.472 0.724 152
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 0.91 0.459 0.759 152
SKI P12755 SKI proto-oncogene 1.00 0.545 0.690 149
CHST3 Q7LGC8 carbohydrate sulfotransferase 3 8.5E-03 0.534 0.690 148
RMRP RNA component of mitochondrial RNA processing endoribonuclease 0.586 0.655 147
PTCH1 Q13635 patched 1 1.00 0.435 0.759 146
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.561 0.655 145
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 7.7E-04 0.534 0.690 142
ARX Q96QS3 aristaless related homeobox 0.91 0.541 0.448 142
NOTCH3 Q9UM47 notch 3 0.87 0.469 0.690 141
POR P16435 cytochrome p450 oxidoreductase 7.4E-09 0.554 0.586 141
SLC26A2 P50443 solute carrier family 26 member 2 6.7E-07 0.600 0.552 138