Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 34
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 17
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 37
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 48
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 27
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 24
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885 9
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846 1
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 15
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846 34
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808 21
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885 34
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885 27
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769 8
CD59 P13987 CD59 molecule (CD59 blood group) 0.61 0.469 0.808 11
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808 10
CX3CL1 P78423 C-X3-C motif chemokine ligand 1 Signaling 0.61 0.478 0.808 27
ITGB3 P05106 integrin subunit beta 3 Receptor 1.7E-03 0.485 0.846 13
PDGFB P01127 platelet derived growth factor subunit B Signaling 0.77 0.488 0.846 17
AXL P30530 AXL receptor tyrosine kinase Kinase 1.3E-02 0.489 0.615 2