Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
ALOX15 P16050 arachidonate 15-lipoxygenase Enzyme 1.1E-23 0.502 0.846 4
C6 P13671 complement C6 5.9E-22 0.700 0.615 6
TBXAS1 P24557 thromboxane A synthase 1 1.4E-20 0.619 0.615 12
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 27
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769 8
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 24
COL4A3 Q01955 collagen type IV alpha 3 chain 1.1E-12 0.552 0.692 4
LTBP1 Q14766 latent transforming growth factor beta binding protein 1 Calcium-binding protein 3.7E-09 0.670 0.500 3
PLEKHA7 Q6IQ23 pleckstrin homology domain containing A7 6.2E-09 0.729 0.423 3
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
ITGA3 P26006 integrin subunit alpha 3 3.6E-07 0.573 0.731 5
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808 17
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 17
RNLS Q5VYX0 renalase, FAD dependent amine oxidase 3.8E-06 0.678 0.423 6
PRF1 P14222 perforin 1 5.5E-06 0.540 0.692 7
RGS2 P41220 regulator of G protein signaling 2 Enzyme modulator 5.7E-06 0.561 0.769 7
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846 1
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846 34
LTC4S Q16873 leukotriene C4 synthase Enzyme 8.5E-04 0.647 0.731 4
CCL7 P80098 C-C motif chemokine ligand 7 Signaling 8.9E-04 0.548 0.846 8
PDGFD Q9GZP0 platelet derived growth factor D Signaling 1.7E-03 0.579 0.538 6
ITGB3 P05106 integrin subunit beta 3 Receptor 1.7E-03 0.485 0.846 13