Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 34
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 17
TBXAS1 P24557 thromboxane A synthase 1 1.4E-20 0.619 0.615 12
CD59 P13987 CD59 molecule (CD59 blood group) 0.61 0.469 0.808 11
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808 10
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769 8
PRF1 P14222 perforin 1 5.5E-06 0.540 0.692 7
RNLS Q5VYX0 renalase, FAD dependent amine oxidase 3.8E-06 0.678 0.423 6
C6 P13671 complement C6 5.9E-22 0.700 0.615 6
ITGA3 P26006 integrin subunit alpha 3 3.6E-07 0.573 0.731 5
COL4A3 Q01955 collagen type IV alpha 3 chain 1.1E-12 0.552 0.692 4
PLEKHA7 Q6IQ23 pleckstrin homology domain containing A7 6.2E-09 0.729 0.423 3
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808 17
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 15
LTBP1 Q14766 latent transforming growth factor beta binding protein 1 Calcium-binding protein 3.7E-09 0.670 0.500 3
GJA5 P36382 gap junction protein alpha 5 Cell-cell junction 1.8E-02 0.575 0.577 11
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 27
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 24
ALOX5AP P20292 arachidonate 5-lipoxygenase activating protein Enzyme 7.1E-02 0.612 0.731 6
ALOX15 P16050 arachidonate 15-lipoxygenase Enzyme 1.1E-23 0.502 0.846 4
LTC4S Q16873 leukotriene C4 synthase Enzyme 8.5E-04 0.647 0.731 4