Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2132 21
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1604 22
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1533 21
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1410 15
IFNG P01579 interferon gamma 0.47 0.288 0.962 1361 10
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 1214 67
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1156 29
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1050 26
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 1034 19
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 1030 52
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923 1029 4
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 932 19
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 926 22
IL2 P60568 interleukin 2 0.48 0.336 0.885 894 4
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 886 50
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 816 57
LEP P41159 leptin 0.46 0.349 0.846 807 13
H3P10 H3 histone pseudogene 10 0.350 0.846 769 0
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 717 26
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 715 13
MIR21 microRNA 21 0.363 0.846 705 2
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 704 15
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962 703 0
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 702 42