Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SOAT2 O75908 sterol O-acyltransferase 2 Enzyme 5.6E-28 0.716 0.308 4
GTPBP4 Q9BZE4 GTP binding protein 4 1.00 0.769 0.346 2
SLC34A1 Q06495 solute carrier family 34 member 1 Transporter 8.9E-27 0.619 0.423 10
DGAT2 Q96PD7 diacylglycerol O-acyltransferase 2 Enzyme 8.4E-12 0.686 0.423 7
RNLS Q5VYX0 renalase, FAD dependent amine oxidase 3.8E-06 0.678 0.423 6
PCSK2 P16519 proprotein convertase subtilisin/kexin type 2 Enzyme 1.00 0.663 0.462 5
MFN1 Q8IWA4 mitofusin 1 Enzyme 2.5E-10 0.644 0.577 10
SREBF2 Q12772 sterol regulatory element binding transcription factor 2 0.21 0.566 0.577 9
C6 P13671 complement C6 5.9E-22 0.700 0.615 6
DGAT1 O75907 diacylglycerol O-acyltransferase 1 Enzyme 1.4E-17 0.621 0.615 3
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654 19
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654 6
CBR1 P16152 carbonyl reductase 1 6.3E-05 0.572 0.654 3
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 18
EPOR P19235 erythropoietin receptor Receptor 1.0E-02 0.526 0.692 17
LPIN1 Q14693 lipin 1 6.5E-13 0.601 0.692 5
ACAT1 P24752 acetyl-CoA acetyltransferase 1 Enzyme 9.9E-08 0.538 0.692 3
SLC19A2 O60779 solute carrier family 19 member 2 Transporter 4.3E-04 0.636 0.692 2
SLC19A3 Q9BZV2 solute carrier family 19 member 3 Transporter 0.10 0.610 0.692 2
SLC19A1 P41440 solute carrier family 19 member 1 Transporter 6.5E-06 0.523 0.692 1
PTGER4 P35408 prostaglandin E receptor 4 G-protein coupled receptor 0.98 0.558 0.731 14
BNIP3 Q12983 BCL2 interacting protein 3 2.0E-05 0.520 0.731 14
ARG2 P78540 arginase 2 Enzyme 1.8E-04 0.569 0.731 10
ADIPOR2 Q86V24 adiponectin receptor 2 Receptor 0.36 0.564 0.731 6