Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808 16
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
SOAT2 O75908 sterol O-acyltransferase 2 Enzyme 5.6E-28 0.716 0.308 4
SLC34A1 Q06495 solute carrier family 34 member 1 Transporter 8.9E-27 0.619 0.423 10
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769 20
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846 38
C6 P13671 complement C6 5.9E-22 0.700 0.615 6
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846 14
DGAT1 O75907 diacylglycerol O-acyltransferase 1 Enzyme 1.4E-17 0.621 0.615 3
LPIN1 Q14693 lipin 1 6.5E-13 0.601 0.692 5
SLC22A2 O15244 solute carrier family 22 member 2 Transporter 2.0E-12 0.572 0.769 9
DGAT2 Q96PD7 diacylglycerol O-acyltransferase 2 Enzyme 8.4E-12 0.686 0.423 7
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 41
MFN1 Q8IWA4 mitofusin 1 Enzyme 2.5E-10 0.644 0.577 10
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 26
POSTN Q15063 periostin Signaling 1.1E-09 0.428 0.885 14
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 40
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808 17
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 26
DDC P20711 dopa decarboxylase 3.8E-08 0.535 0.769 9
BGLAP P02818 bone gamma-carboxyglutamate protein 4.6E-08 0.462 0.846 13
ACAT1 P24752 acetyl-CoA acetyltransferase 1 Enzyme 9.9E-08 0.538 0.692 3
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654 19
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 72