Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 109 1
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731 108 72
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 103 4
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 101 18
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885 100 3
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 99 10
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 98 61
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 96 6
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 95 596
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 95 5
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 92 30
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 91 10
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 90 28
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 89 14
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 89 2
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 89 1
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 83 37
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 82 6
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 81 2
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 80 3
IL2 P60568 interleukin 2 0.48 0.336 0.885 75 3
CDH1 P12830 cadherin 1 0.15 0.401 0.808 73 158
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 73 19
ALAD P13716 aminolevulinate dehydratase Enzyme 5.6E-05 0.556 0.615 73 6