Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PLA2G4A P47712 phospholipase A2 group IVA Enzyme 6.0E-05 0.496 0.846 16
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 15
TACR1 P25103 tachykinin receptor 1 G-protein coupled receptor 3.8E-04 0.502 0.885 15
CD40 P25942 CD40 molecule 0.85 0.396 0.846 14
FGA P02671 fibrinogen alpha chain 1.2E-13 0.573 0.769 14
IL5 P05113 interleukin 5 5.7E-03 0.437 0.846 14
RHOA P61586 ras homolog family member A Enzyme modulator 0.60 0.502 0.808 14
C5AR1 P21730 complement C5a receptor 1 G-protein coupled receptor 0.40 0.513 0.808 11
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808 11
MUC5AC P98088 mucin 5AC, oligomeric mucus/gel-forming Enzyme modulator 1.0E-08 0.483 0.808 10
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923 10
UTS2 O95399 urotensin 2 3.2E-02 0.564 0.808 10
CD86 P42081 CD86 molecule 0.95 0.483 0.769 9
SFTPD P35247 surfactant protein D Surfactant 7.5E-05 0.500 0.846 9
VIP P01282 vasoactive intestinal peptide Signaling 4.2E-04 0.437 0.846 9
C5 P01031 complement C5 Enzyme modulator 8.1E-24 0.550 0.731 8
PTGER3 P43115 prostaglandin E receptor 3 G-protein coupled receptor 0.37 0.601 0.731 8
TLR3 O15455 toll like receptor 3 Receptor 1.6E-07 0.427 0.885 8
CARM1 Q86X55 coactivator associated arginine methyltransferase 1 Epigenetic regulator 1.00 0.601 0.692 7
ITPR1 Q14643 inositol 1,4,5-trisphosphate receptor type 1 Ion channel 1.00 0.534 0.846 7
CCL22 O00626 C-C motif chemokine ligand 22 Signaling 8.4E-03 0.500 0.846 6
SFTPA1 Q8IWL2 surfactant protein A1 3.7E-04 0.546 0.808 6
SFTPB P07988 surfactant protein B 2.6E-04 0.575 0.654 6
SLC22A1 O15245 solute carrier family 22 member 1 Transporter 1.5E-22 0.556 0.731 6