Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 765 17
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846 762 56
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962 762 4
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 757 66
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 748 8
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 747 8
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 739 21
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 722 20
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 717 26
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 715 13
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 706 18
MIR21 microRNA 21 0.363 0.846 705 2
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 704 15
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962 703 0
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 702 42
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 698 51
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923 681 20
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 673 18
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 671 5
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846 669 28
REN P00797 renin Enzyme 2.4E-07 0.370 0.923 668 14
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 665 33
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 664 32
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808 663 1