Source: PSYGENET

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808 26
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577 13
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808 12
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 10
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 10
ALDH2 P05091 aldehyde dehydrogenase 2 family member Enzyme 3.4E-10 0.457 0.885 7
GRIK1 P39086 glutamate ionotropic receptor kainate type subunit 1 Ion channel 1.2E-09 0.641 0.462 7
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 7
ADH1B P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 9.9E-07 0.502 0.846 6
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 6
GABRA1 P14867 gamma-aminobutyric acid type A receptor subunit alpha1 Ion channel 0.91 0.563 0.577 6
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923 6
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 6
REN P00797 renin Enzyme 2.4E-07 0.370 0.923 6
FYN P06241 FYN proto-oncogene, Src family tyrosine kinase Kinase 0.99 0.556 0.731 5
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 5
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 5
AKR1A1 P14550 aldo-keto reductase family 1 member A1 Enzyme 6.7E-07 0.510 0.846 4
ALDH1A1 P00352 aldehyde dehydrogenase 1 family member A1 Enzyme 0.95 0.460 0.846 4
CHAT P28329 choline O-acetyltransferase Enzyme 5.6E-11 0.520 0.808 4
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 4
ADH1C P00326 alcohol dehydrogenase 1C (class I), gamma polypeptide Enzyme 0.547 0.731 3
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 3
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923 2