Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 14
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 13
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923 9
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 6
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 4
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 4
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 3
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 2
BARD1 Q99728 BRCA1 associated RING domain 1 1.4E-24 0.597 0.538 1
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 1
ESPL1 Q14674 extra spindle pole bodies like 1, separase Enzyme 1.00 0.647 0.462 1
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 1
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731 1
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885 1
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885 1
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885 1
WNT1 P04628 Wnt family member 1 Signaling 0.33 0.495 0.769 1