Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TSBP1-AS1 TSBP1 and BTNL2 antisense RNA 1 0.638 0.692 39 318
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 37 18
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 32 28
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769 27 62
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 26 135
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 26 8
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692 25 99
CDKAL1 Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 1.6E-02 0.617 0.615 24 100
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 22 36
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 22 20
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538 22 18
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769 21 151
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 19 64
HECTD4 Q9Y4D8 HECT domain E3 ubiquitin protein ligase 4 1.00 0.700 0.462 19 5
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 16 16
ALDH1A2 O94788 aldehyde dehydrogenase 1 family member A2 Enzyme 0.36 0.578 0.692 14 220
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462 14 21
HCP5 Q6MZN7 HLA complex P5 0.595 0.808 14 16
SFTA2 Q6UW10 surfactant associated 2 3.6E-02 0.695 0.577 14 9
CHRNA3 P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 1.4E-07 0.588 0.692 13 17
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731 13 10
HNF1A-AS1 HNF1A antisense RNA 1 0.621 0.538 13 10
MUCL3 Q3MIW9 mucin like 3 1.2E-05 0.691 0.731 13 8
NAA25 Q14CX7 N-alpha-acetyltransferase 25, NatB auxiliary subunit Enzyme 1.00 0.603 0.692 13 3