Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 75
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 46
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808 17
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846 15
HCN1 O60741 hyperpolarization activated cyclic nucleotide gated potassium channel 1 1.00 0.564 0.654 14
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808 14
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769 13
MBP P02686 myelin basic protein 0.28 0.510 0.885 11
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846 10
MAP2 P11137 microtubule associated protein 2 1.00 0.537 0.692 9
KCNA1 Q09470 potassium voltage-gated channel subfamily A member 1 Ion channel 7.6E-02 0.573 0.577 8
ADK P55263 adenosine kinase Kinase 3.1E-04 0.584 0.769 7
GLUD1 P00367 glutamate dehydrogenase 1 Enzyme 7.0E-03 0.584 0.731 7
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 6
DBN1 Q16643 drebrin 1 Cellular structure 1.00 0.633 0.538 6
FYN P06241 FYN proto-oncogene, Src family tyrosine kinase Kinase 0.99 0.556 0.731 6
PRICKLE1 Q96MT3 prickle planar cell polarity protein 1 Cellular structure 1.00 0.647 0.615 6
PTPRZ1 P23471 protein tyrosine phosphatase receptor type Z1 Enzyme 0.99 0.623 0.615 6
SLC6A1 P30531 solute carrier family 6 member 1 Transporter 1.00 0.592 0.538 6
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923 5
DLG4 P78352 discs large MAGUK scaffold protein 4 Receptor 1.00 0.595 0.654 5
DTNBP1 Q96EV8 dystrobrevin binding protein 1 6.8E-06 0.588 0.615 4