Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 48
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 37
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846 34
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 34
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885 34
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
CX3CL1 P78423 C-X3-C motif chemokine ligand 1 Signaling 0.61 0.478 0.808 27
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885 27
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 27
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 24
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808 22
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808 21
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808 17
PDGFB P01127 platelet derived growth factor subunit B Signaling 0.77 0.488 0.846 17
PTAFR P25105 platelet activating factor receptor G-protein coupled receptor 0.24 0.575 0.731 17
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 17
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 15
ITGB3 P05106 integrin subunit beta 3 Receptor 1.7E-03 0.485 0.846 13
TBXAS1 P24557 thromboxane A synthase 1 1.4E-20 0.619 0.615 12
CD59 P13987 CD59 molecule (CD59 blood group) 0.61 0.469 0.808 11
GJA5 P36382 gap junction protein alpha 5 Cell-cell junction 1.8E-02 0.575 0.577 11