Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 382
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 286
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 229
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 221
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 218
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846 218
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 216
POLR3A O14802 RNA polymerase III subunit A Enzyme 1.3E-23 0.538 0.769 198
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 192
PHGDH O43175 phosphoglycerate dehydrogenase Enzyme 1.3E-04 0.484 0.885 159
NSD1 Q96L73 nuclear receptor binding SET domain protein 1 Epigenetic regulator 1.00 0.505 0.769 158
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808 151
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808 149
CC2D2A Q9P2K1 coiled-coil and C2 domain containing 2A 1.7E-27 0.532 0.692 142
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 142
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808 138
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 135
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769 131
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808 128
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 122
DKC1 O60832 dyskerin pseudouridine synthase 1 Nucleic acid binding 1.00 0.547 0.769 116
AUTS2 Q8WXX7 activator of transcription and developmental regulator AUTS2 1.00 0.569 0.846 112
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846 111
KCNH1 O95259 potassium voltage-gated channel subfamily H member 1 Ion channel 0.55 0.542 0.731 110