Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769 16
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808 12
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654 12
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846 10
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769 10
FKBP5 Q13451 FKBP prolyl isomerase 5 Enzyme 0.73 0.524 0.769 10
LEP P41159 leptin 0.46 0.349 0.846 10
SAT1 P21673 spermidine/spermine N1-acetyltransferase 1 0.87 0.539 0.808 10
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 8
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 7
CCKAR P32238 cholecystokinin A receptor G-protein coupled receptor 4.0E-03 0.615 0.500 7
GLUL P15104 glutamate-ammonia ligase Enzyme 1.00 0.513 0.731 7
GRIK4 Q16099 glutamate ionotropic receptor kainate type subunit 4 Ion channel 0.11 0.678 0.423 7
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769 7
TDO2 P48775 tryptophan 2,3-dioxygenase Enzyme 2.0E-10 0.599 0.654 7
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 6
ADH1B P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 9.9E-07 0.502 0.846 6
ANK3 Q12955 ankyrin 3 1.00 0.578 0.654 6
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 6
HDAC2 Q92769 histone deacetylase 2 Epigenetic regulator 1.00 0.476 0.846 6
ME2 P23368 malic enzyme 2 Enzyme 3.0E-15 0.705 0.346 6
NPAS3 Q8IXF0 neuronal PAS domain protein 3 Transcription factor 1.00 0.729 0.269 6
PCNT O95613 pericentrin 4.0E-58 0.564 0.808 6
PPP3CC P48454 protein phosphatase 3 catalytic subunit gamma 0.26 0.769 0.192 6