Source: GENOMICS_ENGLAND

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
COL4A1 P02462 collagen type IV alpha 1 chain 1.00 0.484 0.731 21
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 20
SLC5A6 Q9Y289 solute carrier family 5 member 6 Transporter 6.1E-03 0.674 0.577 18
WDR37 Q9Y2I8 WD repeat domain 37 0.57 0.751 0.231 14
TREX1 Q9NSU2 three prime repair exonuclease 1 0.58 0.517 0.808 13
VAMP2 P63027 vesicle associated membrane protein 2 0.89 0.650 0.462 13
ZNF292 O60281 zinc finger protein 292 Enzyme 1.00 0.695 0.423 12
CDK8 P49336 cyclin dependent kinase 8 Kinase 0.41 0.597 0.654 11
PIGB Q92521 phosphatidylinositol glycan anchor biosynthesis class B Enzyme 3.9E-11 0.839 0.038 11
RARS1 P54136 arginyl-tRNA synthetase 1 3.3E-08 0.604 0.538 11
APC2 O95996 APC regulator of WNT signaling pathway 2 1.00 0.582 0.654 10
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808 10
RNF13 O43567 ring finger protein 13 4.0E-04 0.722 0.346 10
TRAPPC4 Q9Y296 trafficking protein particle complex 4 Transporter 4.1E-06 0.805 0.308 10
ZMIZ1 Q9ULJ6 zinc finger MIZ-type containing 1 1.00 0.588 0.615 10
ATN1 P54259 atrophin 1 1.00 0.409 0.885 9
FH P07954 fumarate hydratase Enzyme 8.8E-02 0.489 0.846 9
GOT2 P00505 glutamic-oxaloacetic transaminase 2 1.4E-02 0.529 0.731 9
LSS P48449 lanosterol synthase 1.8E-07 0.606 0.654 9
P4HTM Q9NXG6 prolyl 4-hydroxylase, transmembrane 3.9E-09 0.666 0.500 9
DLL1 O00548 delta like canonical Notch ligand 1 1.00 0.492 0.808 8
FDFT1 P37268 farnesyl-diphosphate farnesyltransferase 1 4.1E-15 0.621 0.615 8
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 8
MED12L Q86YW9 mediator complex subunit 12L Transcription factor 1.00 0.839 0.269 8