Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808 15
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846 12
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 7
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 5
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923 4
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808 4
CDK2 P24941 cyclin dependent kinase 2 Kinase 0.61 0.456 0.692 3
MYD88 Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 0.12 0.414 0.923 3
SPEN Q96T58 spen family transcriptional repressor 1.00 0.644 0.654 3
CD79A P11912 CD79a molecule Receptor 0.69 0.536 0.731 2
CD79B P40259 CD79b molecule Receptor 0.92 0.576 0.577 2
IKZF1 Q13422 IKAROS family zinc finger 1 Transcription factor 1.00 0.533 0.769 2
CARD11 Q9BXL7 caspase recruitment domain family member 11 1.00 0.582 0.615 1
FBXO11 Q86XK2 F-box protein 11 Enzyme 1.00 0.604 0.692 1
FOXO1 Q12778 forkhead box O1 1.00 0.433 0.846 1
GNA13 Q14344 G protein subunit alpha 13 Enzyme modulator 0.87 0.656 0.538 1
IRF8 Q02556 interferon regulatory factor 8 Transcription factor 0.95 0.539 0.808 1
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885 1
PRDM1 O75626 PR/SET domain 1 0.96 0.538 0.731 1
SGK1 O00141 serum/glucocorticoid regulated kinase 1 Kinase 2.3E-03 0.506 0.769 1
STAT6 P42226 signal transducer and activator of transcription 6 Nucleic acid binding 0.99 0.475 0.808 1
TRAF5 O00463 TNF receptor associated factor 5 Signaling 1.7E-12 0.659 0.654 1