Source: PSYGENET

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808 26
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 16
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769 16
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 14
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577 13
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 13
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692 12
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808 12
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654 12
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808 11
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 11
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885 11
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 10
CNR2 P34972 cannabinoid receptor 2 G-protein coupled receptor 6.5E-06 0.509 0.846 8
GAL P22466 galanin and GMAP prepropeptide 4.4E-06 0.493 0.846 8
ALDH2 P05091 aldehyde dehydrogenase 2 family member Enzyme 3.4E-10 0.457 0.885 7
ADH1B P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 9.9E-07 0.502 0.846 6
GABRA1 P14867 gamma-aminobutyric acid type A receptor subunit alpha1 Ion channel 0.91 0.563 0.577 6
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 5
FYN P06241 FYN proto-oncogene, Src family tyrosine kinase Kinase 0.99 0.556 0.731 5
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 5
MPDZ O75970 multiple PDZ domain crumbs cell polarity complex component 5.8E-38 0.638 0.500 5
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 5
AKR1A1 P14550 aldo-keto reductase family 1 member A1 Enzyme 6.7E-07 0.510 0.846 4