Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 37 18
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 30 202
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769 27 62
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692 25 99
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 22 20
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538 22 18
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 19 64
LINC02571 long intergenic non-protein coding RNA 2571 0.743 0.500 18 42
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 16 16
ALDH1A2 O94788 aldehyde dehydrogenase 1 family member A2 Enzyme 0.36 0.578 0.692 14 220
TMEM258 P61165 transmembrane protein 258 1.9E-03 0.644 0.654 14 28
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462 14 21
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885 14 12
JMJD1C Q15652 jumonji domain containing 1C 1.00 0.517 0.769 13 20
UGT1A8 Q9HAW9 UDP glucuronosyltransferase family 1 member A8 1.3E-09 0.588 0.654 12 284
UGT1A10 Q9HAW8 UDP glucuronosyltransferase family 1 member A10 4.6E-19 0.588 0.615 12 264
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731 12 69
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808 12 32
MYRF Q9Y2G1 myelin regulatory factor 1.00 0.584 0.731 12 32
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846 12 32
NECTIN2 Q92692 nectin cell adhesion molecule 2 0.97 0.575 0.769 12 29
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885 12 22
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769 12 7
UGT1A9 O60656 UDP glucuronosyltransferase family 1 member A9 5.4E-08 0.590 0.577 11 227