Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 234
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 128
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 111
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 109
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885 102
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 99
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885 95
TRH P20396 thyrotropin releasing hormone 8.9E-04 0.519 0.846 95
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 92
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 67
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885 51
SST P61278 somatostatin Signaling 0.34 0.399 0.885 51
SLC1A1 P43005 solute carrier family 1 member 1 Transporter 8.7E-06 0.561 0.654 48
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885 47
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 40
LTF P02788 lactotransferrin Enzyme 1.3E-21 0.543 0.846 37
ACTA2 P62736 actin alpha 2, smooth muscle Cellular structure 0.93 0.508 0.846 36
CXCL9 Q07325 C-X-C motif chemokine ligand 9 Signaling 2.9E-03 0.462 0.808 35
RARB P10826 retinoic acid receptor beta Nuclear receptor 1.00 0.478 0.846 35
SELENOP P49908 selenoprotein P Extracellular structure 8.3E-07 0.545 0.769 35
AREG P15514 amphiregulin Signaling 0.35 0.487 0.769 32
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769 30
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 28
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923 28