Source: GWASCAT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 100 16
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 79 13
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692 74 50
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 74 8
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769 69 53
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 64 61
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 53 30
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 50 31
ALDH1A2 O94788 aldehyde dehydrogenase 1 family member A2 Enzyme 0.36 0.578 0.692 45 46
ACOXL Q9NUZ1 acyl-CoA oxidase like Enzyme 5.2E-15 0.674 0.577 40 44
TMEM258 P61165 transmembrane protein 258 1.9E-03 0.644 0.654 40 13
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808 38 29
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 38 13
SLC39A8 Q9C0K1 solute carrier family 39 member 8 Transporter 0.67 0.584 0.769 38 8
MYRF Q9Y2G1 myelin regulatory factor 1.00 0.584 0.731 37 13
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462 36 16
CUX2 O14529 cut like homeobox 2 Transcription factor 1.00 0.644 0.500 36 10
JMJD1C Q15652 jumonji domain containing 1C 1.00 0.517 0.769 35 48
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 33 42
ZFHX3 Q15911 Q6ZP98 zinc finger homeobox 3 0.45 0.621 0.654 32 34
UBE2L3 P68036 ubiquitin conjugating enzyme E2 L3 Enzyme 0.84 0.644 0.615 32 25
CPS1 P31327 carbamoyl-phosphate synthase 1 Enzyme 1.1E-09 0.590 0.615 32 5
HECTD4 Q9Y4D8 HECT domain E3 ubiquitin protein ligase 4 1.00 0.700 0.462 31 11
SIK3 Q9Y2K2 SIK family kinase 3 Kinase 1.00 0.631 0.654 28 20