Source: GWASDB

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 37 18
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692 25 99
CDKAL1 Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 1.6E-02 0.617 0.615 24 100
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 22 20
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538 22 18
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 19 64
HECTD4 Q9Y4D8 HECT domain E3 ubiquitin protein ligase 4 1.00 0.700 0.462 19 5
ALDH1A2 O94788 aldehyde dehydrogenase 1 family member A2 Enzyme 0.36 0.578 0.692 14 220
TMEM258 P61165 transmembrane protein 258 1.9E-03 0.644 0.654 14 28
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462 14 21
PRKAG2 Q9UGJ0 protein kinase AMP-activated non-catalytic subunit gamma 2 Enzyme modulator 1.00 0.582 0.654 14 16
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731 12 69
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808 12 32
MYRF Q9Y2G1 myelin regulatory factor 1.00 0.584 0.731 12 32
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846 12 32
NECTIN2 Q92692 nectin cell adhesion molecule 2 0.97 0.575 0.769 12 29
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769 12 7
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 11 61
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846 11 11
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769 11 11
UBE2L3 P68036 ubiquitin conjugating enzyme E2 L3 Enzyme 0.84 0.644 0.615 10 24
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846 10 18
FAM13A O94988 family with sequence similarity 13 member A 1.9E-18 0.653 0.462 10 12
CUBN O60494 cubilin 4.6E-42 0.587 0.769 10 9