Source: GWASCAT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 79 13
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692 74 50
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 64 61
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 61 54
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 53 30
ACOXL Q9NUZ1 acyl-CoA oxidase like Enzyme 5.2E-15 0.674 0.577 40 44
MIR4435-2HG MIR4435-2 host gene 0.604 0.692 38 56
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808 38 29
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 38 13
SLC39A8 Q9C0K1 solute carrier family 39 member 8 Transporter 0.67 0.584 0.769 38 8
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462 36 16
UBE2L3 P68036 ubiquitin conjugating enzyme E2 L3 Enzyme 0.84 0.644 0.615 32 25
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846 32 19
CPS1 P31327 carbamoyl-phosphate synthase 1 Enzyme 1.1E-09 0.590 0.615 32 5
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731 30 48
ZFPM2 Q8WW38 zinc finger protein, FOG family member 2 Transcription factor 1.00 0.565 0.731 30 27
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846 30 9
MARK4 Q96L34 microtubule affinity regulating kinase 4 Kinase 1.00 0.641 0.615 28 44
BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor 1.4E-04 0.716 0.538 28 32
SIK3 Q9Y2K2 SIK family kinase 3 Kinase 1.00 0.631 0.654 28 20
RMI2 Q96E14 RecQ mediated genome instability 2 1.9E-02 0.666 0.500 28 19
PNKD Q8N490 PNKD metallo-beta-lactamase domain containing 4.1E-08 0.615 0.615 28 17
CLPTM1L Q96KA5 CLPTM1 like Enzyme 4.4E-05 0.551 0.654 28 11
PLCL2 Q9UPR0 phospholipase C like 2 Enzyme 1.00 0.743 0.308 27 28