| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases | Num. SNPs |
|---|---|---|---|---|---|---|---|---|
| TWIST1 | Q15672 | twist family bHLH transcription factor 1 | Transcription factor | 0.34 | 0.397 | 0.846 | 559 | 31 |
| CHD7 | Q9P2D1 | chromodomain helicase DNA binding protein 7 | 1.00 | 0.441 | 0.846 | 419 | 247 | |
| SIX1 | Q15475 | SIX homeobox 1 | Transcription factor | 0.65 | 0.496 | 0.692 | 200 | 12 |
| EFNB1 | P98172 | ephrin B1 | Signaling | 0.93 | 0.561 | 0.769 | 134 | 19 |
| ALX4 | Q9H161 | ALX homeobox 4 | 0.36 | 0.560 | 0.692 | 129 | 18 | |
| ALX3 | O95076 | ALX homeobox 3 | 1.9E-02 | 0.578 | 0.692 | 91 | 7 | |
| SIX2 | Q9NPC8 | SIX homeobox 2 | Transcription factor | 0.94 | 0.604 | 0.654 | 79 | 1 |
| ALX1 | Q15699 | ALX homeobox 1 | 0.18 | 0.636 | 0.462 | 59 | 1 |