Source: HPO

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846 205
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808 180
NGLY1 Q96IV0 N-glycanase 1 Enzyme 1.5E-13 0.601 0.654 124
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 119
TBL1XR1 Q9BZK7 TBL1X receptor 1 1.00 0.534 0.808 91
SLC7A7 Q9UM01 solute carrier family 7 member 7 Transporter 8.0E-07 0.603 0.654 84
ANK1 P16157 ankyrin 1 1.00 0.540 0.885 65
CFH P08603 complement factor H 0.86 0.441 0.885 62
CFI P05156 complement factor I 3.5E-08 0.569 0.731 61
ZBTB16 Q05516 zinc finger and BTB domain containing 16 Transcription factor 1.00 0.545 0.808 56
SLC4A1 P02730 solute carrier family 4 member 1 (Diego blood group) Transporter 0.85 0.522 0.731 55
PRF1 P14222 perforin 1 5.5E-06 0.540 0.692 48
AHCY P23526 adenosylhomocysteinase Enzyme 3.6E-02 0.582 0.692 42
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808 41
IRF2BP2 Q7Z5L9 interferon regulatory factor 2 binding protein 2 0.85 0.641 0.500 40
NUMA1 Q14980 nuclear mitotic apparatus protein 1 1.00 0.644 0.577 40
RARA P10276 retinoic acid receptor alpha Nuclear receptor 0.96 0.470 0.846 40
SPTA1 P02549 spectrin alpha, erythrocytic 1 2.6E-18 0.638 0.538 40
CD46 P15529 CD46 molecule 4.7E-07 0.477 0.808 39
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846 39
SPTB P11277 spectrin beta, erythrocytic 1.00 0.650 0.462 38
FIP1L1 Q6UN15 factor interacting with PAPOLA and CPSF1 0.79 0.575 0.577 37
NABP1 Q96AH0 nucleic acid binding protein 1 Nucleic acid binding 3.3E-05 0.711 0.423 37
PML P29590 promyelocytic leukemia 0.21 0.477 0.846 37