Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808 26
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 16
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769 16
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 15
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 13
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885 12
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692 12
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808 12
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654 12
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577 11
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885 11
CREB1 P16220 cAMP responsive element binding protein 1 1.00 0.463 0.885 9
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846 9
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769 9
ADRA1A P35348 adrenoceptor alpha 1A G-protein coupled receptor 3.4E-07 0.462 0.846 8
SLC18A2 Q05940 solute carrier family 18 member A2 Transporter 7.6E-02 0.554 0.769 8
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462 7
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846 7
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 7
CHRNB3 Q05901 cholinergic receptor nicotinic beta 3 subunit Ion channel 8.6E-06 0.705 0.308 6
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615 6
PER2 O15055 period circadian regulator 2 Transcription factor 0.71 0.488 0.846 6
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 5
GABRA2 P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 1.00 0.641 0.346 4