BRAF |
P15056
|
B-Raf proto-oncogene, serine/threonine kinase
|
Kinase
|
1.00 |
0.319 |
0.846 |
45
|
TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
39
|
KRAS |
P01116
|
KRAS proto-oncogene, GTPase
|
Enzyme modulator
|
7.9E-04 |
0.320 |
0.923 |
33
|
PIK3CA |
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1.00 |
0.292 |
0.923 |
33
|
HRAS |
P01112
|
HRas proto-oncogene, GTPase
|
Enzyme modulator
|
8.0E-02 |
0.378 |
0.885 |
29
|
PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
27
|
ERBB2 |
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
6.0E-03 |
0.328 |
0.923 |
22
|
AKT1 |
P31749
|
AKT serine/threonine kinase 1
|
Kinase
|
0.98 |
0.311 |
0.962 |
20
|
BRCA2 |
P51587
|
BRCA2 DNA repair associated
|
Nucleic acid binding
|
2.4E-25 |
0.379 |
0.846 |
16
|
NOTCH1 |
P46531
|
notch receptor 1
|
|
1.00 |
0.369 |
0.885 |
16
|
AKT2 |
P31751
|
AKT serine/threonine kinase 2
|
Kinase
|
0.64 |
0.474 |
0.769 |
15
|
NOTCH2 |
Q04721
|
notch receptor 2
|
|
1.00 |
0.441 |
0.808 |
15
|
BAP1 |
Q92560
|
BRCA1 associated protein 1
|
Enzyme
|
0.99 |
0.454 |
0.731 |
14
|
BRCA1 |
P38398
|
BRCA1 DNA repair associated
|
Enzyme
|
9.2E-29 |
0.367 |
0.923 |
14
|
RB1 |
P06400
|
RB transcriptional corepressor 1
|
Nucleic acid binding
|
1.00 |
0.444 |
0.885 |
13
|
EP300 |
Q09472
|
E1A binding protein p300
|
|
1.00 |
0.459 |
0.846 |
12
|
ESR1 |
P03372
|
estrogen receptor 1
|
Nuclear receptor
|
1.00 |
0.324 |
0.962 |
10
|
FGFR1 |
P11362
|
fibroblast growth factor receptor 1
|
Kinase
|
1.00 |
0.362 |
0.885 |
9
|
MAP2K4 |
P45985
|
mitogen-activated protein kinase kinase 4
|
Kinase
|
1.00 |
0.559 |
0.692 |
9
|
CDKN1B |
P46527
|
cyclin dependent kinase inhibitor 1B
|
|
0.62 |
0.409 |
0.769 |
8
|
PALB2 |
Q86YC2
|
partner and localizer of BRCA2
|
|
3.0E-19 |
0.485 |
0.769 |
8
|
ARID1A |
O14497
|
AT-rich interaction domain 1A
|
|
1.00 |
0.455 |
0.846 |
7
|
PIK3CB |
P42338
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
|
Kinase
|
1.00 |
0.322 |
0.885 |
7
|
BRIP1 |
Q9BX63
|
BRCA1 interacting protein C-terminal helicase 1
|
Enzyme
|
6.2E-17 |
0.507 |
0.731 |
6
|