Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 127
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 99
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 97
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885 95
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 89
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 85
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 77
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 67
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 66
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885 66
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 65
CDH1 P12830 cadherin 1 0.15 0.401 0.808 57
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846 57
ENO1 P06733 enolase 1 Enzyme 1.9E-05 0.481 0.885 56
KNG1 P01042 kininogen 1 Enzyme modulator 3.2E-10 0.481 0.885 56
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885 56
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885 51
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 46
TF P02787 transferrin Enzyme 4.1E-08 0.527 0.846 46
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 41
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 41
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885 40
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846 39
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808 35